产品概述
OB-cadherin Rabbit Polyclonal Antibody
Rabbit Polyclonal Antibody
Rabbit
WB,ELISA
Human,Mouse
产品性能
Unconjugated
Unmodified
IgG
Polyclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Affinity purification
免疫原
CDH11
CDH11; Cadherin-11; OSF-4; Osteoblast cadherin; OB-cadherin
1009
P55287
产品应用
WB 1:500-1:2000, ELISA 1:20000.Not yet tested in other applications.
85kDa
研究背景
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008],function:Cadherins are calcium dependent cell adhesion proteins.,function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.,similarity:Contains 5 cadherin domains.,tissue specificity:Expressed mainly in brain but also found in other tissues. Expressed in neuroblasts.,
研究领域
Adherens_Junction
武汉恩玑生命科技有限公司
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