产品概述
Orexin R-1 Rabbit Polyclonal Antibody
Rabbit Polyclonal Antibody
Rabbit
WB,ELISA
Human,Mouse,Rat
产品性能
Unconjugated
Unmodified
IgG
Polyclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Affinity purification
免疫原
HCRTR1
HCRTR1; Orexin receptor type 1; Ox-1-R; Ox1-R; Ox1R; Hypocretin receptor type 1
3061
O43613
产品应用
WB 1:500-1:2000, ELISA 1:5000.Not yet tested in other applications.
50kDa
研究背景
The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B. [provided by RefSeq, Jan 2009],function:Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled to the G(q) subclass of heteromeric G proteins, which activates the phospholipase C mediated signaling cascade.,similarity:Belongs to the G-protein coupled receptor 1 family.,
研究领域
Neuroactive ligand-receptor interaction;
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