产品概述
Rag B Rabbit Polyclonal Antibody
Rabbit Polyclonal Antibody
Rabbit
IHC-P,IF-P,IF-F,ICC/IF,ELISA
Human,Mouse,Rat
产品性能
Unconjugated
Unmodified
IgG
Polyclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Affinity purification
免疫原
RRAGB
RRAGB; Ras-related GTP-binding protein B; Rag B; RagB
10325
Q5VZM2
产品应用
IHC-P 1:100-1:300, ELISA 1:40000, IF-P/IF-F/ICC/IF 1:50-200
研究背景
Ras-homologous GTPases constitute a large family of signal transducers that alternate between an activated, GTP-binding state and an inactivated, GDP-binding state. These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity. All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding, three of which are phosphate-/magnesium-binding sites (PM1-PM3) and three of which are guanine nucleotide-binding sites (G1-G3). Transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008],function:Involved in the RCC1/Ran-GTPase pathway. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity.,similarity:Belongs to the GTR/RAG GTP-binding protein family.,subunit:The short isoform binds GTP (By similarity). Interacts with RRAGC and RRAGD.,
研究领域
mTOR
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