purpactins A

英文别名purpactinA;Aceticacid1-(4-acetyl-11-hydroxy-9-methyl-5-oxo-5H,7H-dibenzo[b,g][1,5]dioxocin-3-yl)-3-methylbutylester;AS-186b;5H,7H-Dibenzo[b,g][1,5]dioxocin-5-one,3-[(1S)-1-(acetyloxy)-3-methylbutyl]-11-hydroxy-4-methoxy-9-methyl-。 Purpactin A has been reported in Talaromyces pinophilus, Penicillium simplicissimum, and Talaromyces flavus with data available. AS-186b is a dibenzodioxocine that is the 1'-O-acetyl derivative of penicillide. It is isolated from Penicillium purpurogenum and acts as an acyl-CoA:cholesterol acyltransferase inhibitor. It has a role as an EC 2.3.1.26 (sterol O-acyltransferase) inhibitor, an antimicrobial agent and a Penicillium metabolite. It is an aromatic ether, a lactone, a member of phenols, an acetate ester and a dibenzodioxocine. It is functionally related to an AS-186a.