【Overview】
A luciferase reporter cell line is a genetically engineered cell system designed to study gene expression and cellular signaling pathways in real-time. These cell lines are stably transfected with a reporter construct where the gene of interest's regulatory elements (e.g., promoter, enhancer, or response elements) control the expression of the luciferase enzyme. When the regulatory elements are activated, luciferase is produced, and its activity can be quantified by measuring light emission (bioluminescence) after adding a luciferin substrate.
【How It Works】
The cell line is exposed to experimental conditions (e.g., drugs, cytokines, or genetic manipulations).
If the pathway of interest is activated, transcription factors bind to the regulatory elements, driving luciferase expression.
Luciferase catalyzes the oxidation of luciferin in the presence of ATP and oxygen, emitting detectable light.
The light signal is measured using a luminometer or imaging system, with intensity proportional to transcriptional activity.
Nebulabio offers Luciferase Reporter Cell Lines for applications including (1)Gene Regulation Studies, (2)Drug Screening,
(3)Signal Transduction Analysis and (4)High-Throughput Assays.
Vicbio Biotechnology Co., Ltd. is an authorized distributor of Nebulabio. Please find the product list below:
| Catalog Number | Product Name | Contact |
| NBST-241001 | NebuTools™ Human TBFbR2 Luciferase HEK293 Cell Line | ☎ Technical Support >> |
| NBST-241002 | NebuTools™ Human Nectin-4 Luciferase MDA-MB-231 Cell Line | ☎ Technical Support >> |
| NBST-241003 | NebuTools™ Human TREM2 Luciferase HEK293 Cell Line | ☎ Technical Support >> |
| NBST-241004 | NebuTools™ Human FcgR2a / CD16a NF-AT Luciferase Jurkat Cell Line | ☎ Technical Support >> |
| NBST-241005 | NebuTools™ Human LAG3 / CD223 NF-AT Luciferase Jurkat Cell Line | ☎ Technical Support >> |
| NBST-241006 | NebuTools™ Human PDCD1 / PD-1 / CD279 NF-AT Luciferase Jurkat Cell Line | ☎ Technical Support >> |
| NBST-241007 | NebuTools™ Human VEGFR2 / KDR / CD309 NF-AT Luciferase HEK293 Cell Line | ☎ Technical Support >> |
| NBST-241008 | NebuTools™ Human CTLA-4 / CD152 NF-AT Luciferase Jurkat Cell Line | ☎ Technical Support >> |
| NBST-241009 | NebuTools™ Human LAG3 & PD-1 NF-AT Luciferase Jurkat Cell Line | ☎ Technical Support >> |
| NBST-241010 | NebuTools™ Human BTLA / CD272 NF-AT Luciferase Jurkat Cell Line | ☎ Technical Support >> |
| NBST-241011 | NebuTools™ Human CD161 NF-AT Luciferase Jurkat Cell Line | ☎ Technical Support >> |
| NBST-241012 | NebuTools™ Human FcgR2a (V158) / CD16a (V158) NF-AT Luciferase Jurkat Cell Line | ☎ Technical Support >> |
| NBST-241013 | NebuTools™ Human FcgR2a (F158) / CD16a (F158) NF-AT Luciferase Jurkat Cell Line | ☎ Technical Support >> |
| NBST-241014 | NebuTools™ Human TIGIT / CD226 NF-AT Luciferase Jurkat Cell Line | ☎ Technical Support >> |
| NBST-241015 | NebuTools™ Human NKG2A & CD94 NF-kB Luciferase Jurkat Cell Line | ☎ Technical Support >> |
| NBST-241016 | NebuTools™ Human TNFRSF9 / 4-1BB / CD137 NF-kB Luciferase CHO Cell Line | ☎ Technical Support >> |
| NBST-241017 | NebuTools™ Human ROR1 & Wnt5a NF-kB Luciferase HEK293 Cell Line | ☎ Technical Support >> |
| NBST-241018 | NebuTools™ Human TREM2 NF-kB Luciferase CHO Cell Line | ☎ Technical Support >> |
| NBST-241019 | NebuTools™ Human IL-1RL1 / ST2 / IL-33R NF-kB Luciferase HEK293 Cell Line | ☎ Technical Support >> |
| NBST-241020 | NebuTools™ Human TNFRSF1B / TNFR2 / CD120b NF-kB Luciferase HEK293 Cell Line | ☎ Technical Support >> |
| NBST-241021 | NebuTools™ Human TREM2 NF-kB Luciferase HEK293 Cell Line | ☎ Technical Support >> |
| NBST-241022 | NebuTools™ Human CXCR4 / CD184 NF-AT Luciferase HEK293 Cell Line | ☎ Technical Support >> |
| NBST-241023 | NebuTools™ Human ROR1 NF-kB Luciferase HEK293 Cell Line | ☎ Technical Support >> |
| NBST-241024 | NebuTools™ Human TNFRSF5 / CD40 NF-kB Luciferase Jurkat Cell Line | ☎ Technical Support >> |
| NBST-241025 | NebuTools™ Human TACTILE / CD96 NF-kB Luciferase Jurkat Cell Line | ☎ Technical Support >> |
| NBST-241026 | NebuTools™ Human TNFRSF18 / GITR / CD357 NF-kB Luciferase Jurkat Cell Line | ☎ Technical Support >> |
| NBST-241027 | NebuTools™ Human TNFRSF1B / TNFR2 / CD120b NF-kB Luciferase Jurkat Cell Line | ☎ Technical Support >> |
| NBST-241028 | NebuTools™ Human TNFRSF9 / 4-1BB / CD137 NF-kB Luciferase Jurkat Cell Line | ☎ Technical Support >> |
| NBST-241029 | NebuTools™ Cynomolgus / Rhesus Macaque CD161 NF-AT Luciferase Jurkat Cell Line | ☎ Technical Support >> |
关键字： Cell-Luciferase Repo;
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