产品信息
宿主
鼠
克隆号
IK22/5
克隆类别
单抗
研究领域
免疫学和肿瘤学,细胞生物学,癌症
The IK22/5 monoclonal antibody reacts with mouse RANKL (receptor activator of nuclear factor kappa-B ligand) also known as CD254 and TRANCE (TNF-related activation-induced cytokine). RANKL is a 35 kDa type II membrane protein that belongs to the TNF superfamily. RANKL is expressed on activated T lymphocytes in the lung, thymus, and lymph nodes and on osteoclasts. RANKL has been implicated in the regulation of T cell and dendritic cell interactions as well as osteoclast differentiation. Additionally, RANKL was found to be critical for osteoclast differentiation.
Isotype
Recommended Isotype Control(s)
Recommended Dilution Buffer
Conjugation
Immunogen
Reported Applications
Formulation
Endotoxin
Purity
Sterility
Production
Purification
RRID
Molecular Weight
Storage
Rat IgG2a, κ
InVivoMAb rat IgG2a isotype control, anti-trinitrophenol
InVivoPure pH 6.5 Dilution Buffer
This product is unconjugated. Conjugation is available via our Antibody Conjugation Services.
NSO-derived recombinant mouse RANKL
in vivo RANKL blockade
PBS, pH 6.5Contains no stabilizers or preservatives
<2EU/mg (<0.002EU/μg)Determined by LAL gel clotting assay
>95%Determined by SDS-PAGE
0.2 µm filtration
Purified from cell culture supernatant in an animal-free facility
Protein G
AB_10949003
150 kDa
The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
组成成分
核因子受体活化因子配体蛋白抗体,磷酸盐缓冲液
上海优宁维生物科技股份有限公司
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