产品详情
| 中文名称:4-溴-3-氟甲苯 | 英文名称:4-Bromo-3-fluorotoluene |
| CAS:452-74-4 | 纯度规格: 98%+ |
| 产品类别: 中间体 |
2026-01-24
4-溴-3-氟甲苯
4-Bromo-3-fluorotoluene
1kg/650RMB;5kg/RMB;100kg/RMB
650
98%+
中间体
4-溴-3-氟甲苯
英文名称：4-Bromo-3-fluorotoluene，又名3-氟-4-溴甲苯，是一种分子式为C7H6BrF的有机化合物，CAS号为452-74-4，分子量189.02500。常温下为无色至淡黄色液体，密度1.494 g/mL（25℃），沸点95℃（50mmHg），闪点95℉，折射率n20/D 1.53
具体用途
该化合物作为有机合成中间体，通过重氮化溴代、Schiemann反应等步骤参与药物合成路径，最终用于生产曲格列汀这类糖尿病治疗药物。其合成路线涉及高温重氮化工艺，可提升生产效率并降低能耗。
物理性质
4-溴-3-氟甲苯为无色透明液体，常温下具有刺激性气味，沸点95℃（50mmHg），密度1.494g/mL（25℃），纯度通常≥98%。
4-Bromo-3-fluorotoluene
English Name: 4-Bromo-3-fluorotoluene, also known as 3-Fluoro-4-bromotoluene, is an organic compound with the molecular formula C₇H₆BrF. Its CAS number is 452-74-4, and its molecular weight is 189.02500. At room temperature, it appears as a colorless to pale yellow liquid, with a density of 1.494 g/mL (at 25°C), a boiling point of 95°C (at 50 mmHg), a flash point of 95°F, and a refractive index of n20/D 1.53.
Specific Applications
This compound serves as an organic synthesis intermediate. It participates in pharmaceutical synthesis pathways through steps such as diazotization bromination and the Schiemann reaction, ultimately used in the production of antidiabetic drugs like Trelegliptin. The synthetic route involves a high-temperature diazotization process, which enhances production efficiency and reduces energy consumption.
Physical Properties
4-Bromo-3-fluorotoluene is a colorless, transparent liquid with a pungent odor at room temperature. It has a boiling point of 95°C (at 50 mmHg), a density of 1.494 g/mL (at 25°C), and a purity typically ≥98%.
关键字： 4-Bromo;452-74-4;曲格列汀中间体;4-溴-3-氟甲苯;3-fluorotoluene;
公司简介
Guangzhou Aanpharm Technology Co.,Ltd was established in may 2018. It is located in Guangzhou, Guangdong Province, in the pearl river rigion close to hongkong&nansha international port also baiyun internationl airport with most convenient and speedy transportation. Aanpharm is a professional company specializing in developing, producing?and marketing of pharmaceutical intermediates.
The company’s products are mainly involved in the field of anti-tumor , epilepsy, rheumatism, cardiovascular and cerebrovascular and have been sold to more than ten countries, such as Europe, India, Japan, South Korea and Southeast Asia. At the present, the company cooperates with three GMP complied factories and two domestic university and R & D center.
Guangzhou Aanpharm Technology Co., Ltd. is a company specialized in developing, manufacturing and marketing of Active Pharmaceutical ingredients (APIs) and their intermediates. The company also offers Custom Synthesis services. Aanpharm has established firmed co-operations with several university and R&D centers. Aanpharm provides high quality products, complete documentation and other outstanding supports to the customers. Customers are based in Europe, India, Korea, Japan and other Southeast Asia.
Why Choose Us
Guangzhou Aanpharm Technology Co., Ltd. is a professional company that specializes in developing, manufacturing, and marketing Active Pharmaceutical Ingredients (APIs) and intermediates. We also provide custom synthesis services to meet our clients’ personalized needs. With advanced technology and equipment, we ensure our products meet the highest quality standards. Our experienced team provides timely and accurate technical support. Choose Aanpharm for innovative solutions and exceptional customer support.
Contact Us
Get in touch with us and let's work together to achieve your goals.
Tel:+86-020-86211473
Mob.:0086-13925088720
Email:sales2@aanpharm.com
Add:no.No.175 jiangtong road, jianggao town,baiyun district, Guangzhou, China
| 成立日期 |
2025-05-07
（1年）
|
注册资本 |
50万人民币
|
| 员工人数 |
10-50人 |
年营业额 |
￥ 1000万-5000万 |
| 主营行业 |
中间体,医药原料 |
经营模式 |
贸易,工厂,试剂,定制,服务 |