Product Name:Pre-S2 (1-26)
CAS No.:104753-45-9
Synonyms:乙型肝炎病毒Pre-S (120-145)
Catalog No.:216P09
Brand:Typeptide Biotech(肽研生物)
Description:Pre-S2 (1-26)是由26个氨基酸组成的多肽,由乙型肝炎病毒(hepatitis B virus, HBV) DNA pre-S2 区域编码的 55 个氨基酸的多肽的 N 端的部分组成。Pre-S2 (1-26) 是一个免疫显性表位,Pre-S2 (1-26) 的免疫原性(immunogenicity)可以通过在其结构上偶联一个脂质体(Liposomes)来增强。由这个抗原决定簇(determinant)诱导产生的抗体可以识别与 HBV 和 HBsAg 共同的包膜表位(envelope epitope)。因为这些抗体在体内具有病毒中和(virusneutralizing)活性,因此 pre-S (120-145) 具有作为抗 HBV 感染的合成疫苗(synthetic vaccine)的潜能。
Pre-S2 (1-26) is a peptide composed of 26 amino acids, forming the N-terminal portion of a 55-amino-acid polypeptide encoded by the pre-S2 region of hepatitis B virus (HBV) DNA. Pre-S2 (1-26) serves as an immunodominant epitope, and its immunogenicity can be enhanced by conjugating it with liposomes. The antibodies induced by this antigenic determinant can recognize a common envelope epitope shared by HBV and HBsAg. Since these antibodies exhibit virus-neutralizing activity in vivo, Pre-S (120-145) holds potential as a synthetic vaccine against HBV infection.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | MQWNSTAFHQTLQDPRVRGLYLPAGG |
Sequence(3-letter code) | H-Met-Gln-Trp-Asn-Ser-Thr-Ala-Phe-His-Gln-Thr-Leu-Gln-Asp-Pro-Arg-Val-Arg-Gly-Leu-Tyr-Leu-Pro-Ala-Gly-Gly-OH |
Peptide Structure | 
|
Molecular Formula | C131H199N39O37S1 |
Molecular Weight | 2944.35 |
订购联系方式:
南京肽研生物生物科技有限公司
手机号:19961912513(微信同号)
QQ: 2178255659
邮箱:sales@typeptide.com
联系人:顾经理
申明:本产品仅供科研使用,不得用于人体。
关键字: 乙型肝炎病毒Pre-S (120-145;104753-45-9;Pre-S2 (1-26);多肽;多肽合成;
肽研生物坐落于国家级新区南京江北新区新材料产业园,是一家专业从事多肽产 品的研发、生产和销售以及多肽技术转让的高新技术企业。公司秉持“诚信、严 谨、务实”的匠人精神,持续投入研发,不断创新,致力于为科研工作者提供丰 富全面的多肽修饰类型和优质的产品。