Product Name：ABT-510
CAS No.：442526-87-6
Synonyms：抗血管生成TSP多肽
Catalog No.：218P438
Brand：Typeptide Biotech（肽研生物）
Description：ABT-510是一种抗血管生成TSP肽 (thrombospondin-1 类似物)，序列中含有9个氨基酸，并且包含两个非天然氨基酸，能诱导肿瘤细胞凋亡并抑制上皮性卵巢癌正位、同种异体模型中的卵巢肿瘤生长。ABT-510还可减少小鼠炎症性肠病模型的血管生成和炎症反应。ABT-510可用于癌症 (尤其是上皮性卵巢癌) 以及炎症性肠病 (IBD) 的研究。
ABT-510 is an anti-angiogenic TSP peptide (thrombospondin-1 analog) with a sequence of nine amino acids, including two non-natural amino acids. It induces tumor cell apoptosis and inhibits ovarian tumor growth in orthotopic and allogeneic models of epithelial ovarian cancer. ABT-510 also reduces angiogenesis and inflammatory responses in mouse models of inflammatory bowel disease. It is applicable for research on cancer (particularly epithelial ovarian cancer) and inflammatory bowel disease (IBD).
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | Ac-Sar-GVIT-Nva-IRP-NHEt |
Sequence(3-letter code) | Ac-Sar-Gly-Val-Ile-Thr-Nva-Ile-Arg-Pro-NHEt |
Peptide Structure | 
|
Molecular Formula | C45H81N13O11 |
Molecular Weight | 980.22 |
订购联系方式：
南京肽研生物生物科技有限公司
手机号：19961912513(微信同号)
QQ: 2178255659
邮箱：sales@typeptide.com
联系人：顾经理
申明：本产品仅供科研使用，不得用于人体。
关键字： ABT-510;抗血管生成TSP多肽;442526-87-6;多肽;多肽合成;
肽研生物坐落于国家级新区南京江北新区新材料产业园，是一家专业从事多肽产 品的研发、生产和销售以及多肽技术转让的高新技术企业。公司秉持“诚信、严 谨、务实”的匠人精神，持续投入研发，不断创新，致力于为科研工作者提供丰 富全面的多肽修饰类型和优质的产品。