(Brontictuzumab)Biosimilar Reference Antibody-GS40105 新品

货号：GS40105

Brontictuzumab (also known as OMP-52M51) is an investigational human monoclonal antibody that was developed as a potential cancer therapy. It functions as a Notch1 inhibitor, designed to block a signaling pathway crucial for the growth and survival of certain cancer cells, particularly cancer stem cells. Clinical trials were conducted to evaluate its efficacy and safety in patients with advanced solid tumors, including colorectal cancer. However, its development appears to have been discontinued, as no significant progress or approvals have been reported in recent years following early-phase studies.