(Dectrekumab)Biosimilar Reference Antibody-GS40172

货号：GS40172

Dectrekumab (QAX576) is an investigational human monoclonal antibody that targets Interleukin-13 (IL-13), a key cytokine in type 2 inflammation, aiming to treat conditions like Eosinophilic Esophagitis (EoE), keloids, and allergic diseases by blocking IL-13's effects. While it showed promise by significantly reducing esophageal eosinophils in EoE trials, it didn't meet primary symptom-relief endpoints, and some trials for other conditions, like keloids, were terminated, making its clinical future uncertain despite its potential for histological improvement.