货号:GS40201
Ebdarokimab is a fully human monoclonal antibody (mAb) designed as an immunomodulatory therapy by targeting the IL-12/IL-23 pathway. It functions by specifically binding to the shared p40 subunit common to both interleukin-12 (IL-12) and interleukin-23 (IL-23), thereby inhibiting the biological activity of these two pro-inflammatory cytokines. This mechanism positions ebdarokimab as a potential treatment for immune-mediated inflammatory diseases where the IL-12/IL-23 axis plays a central role, such as psoriasis, psoriatic arthritis, or inflammatory bowel disease.
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