货号:GS40607
Rilotumumab is a fully human monoclonal antibody targeting hepatocyte growth factor (HGF). It binds to HGF to prevent its interaction with the c-Met receptor, thereby inhibiting the HGF/c-Met signaling pathway involved in tumor growth, angiogenesis, and metastasis. It was investigated for the treatment of advanced solid tumors such as gastric cancer and glioblastoma.
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