(Fulranumab)Biosimilar Reference Antibody-GS40283 新品

货号：GS40283

Fulranumab was an investigational fully human monoclonal antibody developed for chronic pain management, specifically targeting osteoarthritis pain and chronic low back pain. It functioned as a potent and selective nerve growth factor (NGF) inhibitor. By binding to and neutralizing NGF, it blocked its interaction with the TrkA and p75 neurotrophin receptors on sensory neurons, thereby inhibiting the pain-sensitizing signaling cascade responsible for chronic pain states.