(Geptanolimab)Biosimilar Reference Antibody-GS40299

货号：GS40299

Geptanolimab (development code GB-226) is an investigational, fully human monoclonal antibody being developed for cancer immunotherapy. It functions as a programmed cell death-1 (PD-1) checkpoint inhibitor. By binding with high affinity to the PD-1 receptor on the surface of T cells, geptanolimab blocks its interaction with its ligands, PD-L1 and PD-L2. This blockade releases the inhibitory "brake" that PD-1 places on T-cell activation and function, thereby restoring and enhancing the T-cell-mediated anti-tumor immune response. As a fully human antibody, it is designed to minimize immunogenicity.