(Ifabotuzumab)Biosimilar Reference Antibody-GS40326 新品

货号：GS40326

Ifabotuzumab is an immunoglobulin G1 kappa (IgG1κ) monoclonal antibody designed for the treatment of solid tumors, particularly those expressing the target receptor. It is engineered to bind with high affinity to Ephrin type-A receptor 3 (EphA3). A key feature of its design is the intentional lack of fucose on its Fc glycans, a modification that significantly enhances its affinity for the activating Fc gamma receptor IIIa (FcγRIIIa/CD16a) on natural killer (NK) cells and macrophages.