货号:GS40377
Lesofavumab is a human monoclonal antibody developed as a prophylactic agent against respiratory syncytial virus (RSV) infection. It specifically targets a highly conserved epitope on the prefusion conformation of the RSV fusion (F) glycoprotein. By binding to this critical site on the viral surface, lesofavumab neutralizes the virus and prevents it from fusing with and entering host respiratory epithelial cells. It was designed for passive immunization, particularly to protect high-risk infants and young children from severe RSV-associated lower respiratory tract disease, offering an alternative or complement to other preventive strategies like palivizumab.
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