货号:GS40361
Lancastotug (development code AK-127) is a humanized monoclonal antibody that specifically targets TIGIT (T-cell immunoreceptor with Ig and ITIM domains), an inhibitory immune checkpoint receptor. As an antagonist antibody, Lancastotug blocks the interaction between TIGIT and its ligands (such as CD155/PVR), thereby aimed at reversing T-cell and NK-cell exhaustion and restoring anti-tumor immunity. It is currently under clinical investigation as a potential immunotherapeutic agent for the treatment of advanced solid tumors.
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