货号:GS40360
Lanadelumab is a humanized monoclonal antibody that specifically inhibits plasma kallikrein, a key enzyme in the contact system. By blocking kallikrein, it prevents excessive bradykinin production, which is the primary mediator of swelling attacks in hereditary angioedema (HAE). It is approved as a long-term prophylactic treatment to reduce the frequency of HAE attacks.
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