货号:GS40702
Tavolimab is a humanized IgG1 kappa monoclonal antibody targeting tumor necrosis factor receptor superfamily member 4 (TNFRSF4, also known as OX40 or CD134), a co-stimulatory receptor on activated T cells. It acts as an agonist, binding to OX40 to enhance T cell activation, proliferation, and cytokine production, thereby boosting anti-tumor immunity. It is being developed for cancer immunotherapy, often in combination with PD-1/PD-L1 inhibitors, for the treatment of advanced solid tumors.
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