货号:GS40705
Telazorlimab (GBR-830) is a humanized IgG1 kappa monoclonal antibody targeting OX40 (CD134), a co-stimulatory receptor on activated T cells. It functions as an agonist, binding to OX40 to enhance T cell proliferation, cytokine production, and effector function, thereby boosting anti-tumor immunity. It is being developed for cancer immunotherapy, often in combination with checkpoint inhibitors, for the treatment of advanced solid tumors.
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