货号:GS40675
Spesolimab is a humanized monoclonal antibody targeting the interleukin-36 receptor (IL-36R). It binds to IL-36R, blocking the signaling of pro-inflammatory cytokines IL-36α, β, and γ. It is approved for the treatment of generalized pustular psoriasis (GPP) flares in adults, rapidly reducing pustules and systemic inflammation.
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