aladdin 阿拉丁 K120012 犬尿喹啉酸 492-27-3 Moligand?, ≥97%

中文名：犬尿喹啉酸

英文名：Kynurenic acid

应用：An antagonist of NMDA and AMPA/kainate receptors

纯度：Moligand™，≥97%

货号：K120012

Cas号：492-27-3

存储温度：2-8°C储存

运输条件：低温运输

产品介绍：

Kynurenic acid is a metabolite of tryptophan in mammals via the kynurenine pathway. Studies have observed that Kynurenic acid acts as a ligand to the GPR35 G protein-coupled receptor. The binding of Kynurenic acid to GPR35 has been noted to affect calcium mobilization and inositol phosphatase synthesis and may indicate potential signaling functions by Kynurenic acid via the GPR35 receptor. Additionally reported to be a broad spectrum, excitatory amino acid (EAA) antagonist. Other studies have reported that Kynurenic acid acts as an antagonist to mammalian ionotropic glutamate receptors especially NMDA (N-methyl-D-aspartate receptors).Kynurenic acid is an inhibitor of AChR α7, GluR and GlyR.

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