Product Name：Senktide
CAS No.：106128-89-6
Synonyms：速激肽NK-3受体激动剂多肽Senktide
Catalog No.：207P23
Brand：Typeptide Biotech（肽研生物）
Description：Senktide显示出选择性地与速激肽受体亚型(SP-N)相互作用，可用于研究以找出该受体的调节、分布和功能作用。Senktide是速激肽NK-3受体激动剂多肽，序列中包含6个氨基酸，且有一个非天然氨基酸，可能会导致类似于小鼠模型中血清素刺激的行为。已注意到 NK-3R（速激肽 NK-3 受体）可介导豚鼠肺中的支气管收缩，并且Senktide对这些受体的激活也已显示可诱导支气管收缩。 此外，Senktide已证明能够在豚鼠大脑的许多区域诱导更多数量的Fos-LI神经元。
Senktide selectively interacts with the substance P receptor subtype (SP-N) and can be used to study the regulation, distribution, and functional roles of this receptor. Senktide is a peptide agonist of the substance P NK-3 receptor, containing six amino acids with one unnatural amino acid, which may lead to behavioral effects similar to those induced by serotonin stimulation in mouse models. It has been noted that the NK-3R (substance P NK-3 receptor) mediates bronchoconstriction in guinea pig lungs, and activation of these receptors by Senktide has also been shown to induce bronchoconstriction. Additionally, Senktide has been demonstrated to induce a higher number of Fos-LI neurons in various regions of the guinea pig brain.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | Suc-DF-(N-me-Phe)-GLM-NH2 |
Sequence(3-letter code) | Suc-Asp-Phe-(N-me-Phe)-Gly-Leu-Met-NH2 |
Peptide Structure | 
|
Molecular Formula | C40H55N7O11S1 |
Molecular Weight | 841.97 |
订购联系方式：
南京肽研生物生物科技有限公司
手机号：19961912513(微信同号)
QQ: 2178255659
邮箱：sales@typeptide.com
联系人：顾经理
申明：本产品仅供科研使用，不得用于人体。
关键字： Senktide;速激肽NK-3受体激动剂多肽Senkti;106128-89-6;多肽;多肽合成;
肽研生物坐落于国家级新区南京江北新区新材料产业园，是一家专业从事多肽产 品的研发、生产和销售以及多肽技术转让的高新技术企业。公司秉持“诚信、严 谨、务实”的匠人精神，持续投入研发，不断创新，致力于为科研工作者提供丰 富全面的多肽修饰类型和优质的产品。