Lyn A, Human, 重组蛋白 (GST),Lyn A Protein, Human, Recombinant (GST)
  • Lyn A, Human, 重组蛋白 (GST),Lyn A Protein, Human, Recombinant (GST)

Lyn A, Human, 重组蛋白 (GST)|TMPY-04391|TargetMol

价格 585
包装 5μg
最小起订量 5μg
发货地 上海
更新日期 2026-05-08
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产品详情

中文名称:Lyn A, Human, 重组蛋白 (GST)英文名称:Lyn A Protein, Human, Recombinant (GST)
品牌: TargetMol产地: 美国
保存条件: Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months产品类别: 抑制剂
种属: Human表达系统: Baculovirus Insect Cells
蛋白长度: A DNA sequence encoding the human LYN isoform a (NP_002341.1) (Met 1-Pro 512) was fused with the GST tag at the N-terminus. Predicted N terminal: Met标签: N-GST
货号: T011|TMPY-04391
2026-05-08 Lyn A, Human, 重组蛋白 (GST) Lyn A Protein, Human, Recombinant (GST) 5μg/585RMB 585 TargetMol 美国 Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months 抑制剂

Product Introduction

Bioactivity

名称Lyn A Protein, Human, Recombinant (GST)
描述Tyrosine-protein kinase Lyn is a member of the Src family of protein tyrosine kinases, which is mainly expressed in hematopoietic cells, in neural tissues liver, and adipose tissue. Tyrosine-protein kinase Lyn has many functions. Lyn kinase may downregulate the expression of stem cell growth factor receptor (KIT). Lyn kinase Acts as an effector of EpoR (erythropoietin receptor) in controlling KIT expression and may play a central role in erythroid differentiation during the switch between proliferation and maturation. Lyn kinase also acts as a positive regulator of cell movement while negatively regulating adhesion to stromal cells by inhibiting the ICAM-1-binding activity of beta-2 integrins. Lyn kinase relays suppressing signals from the chemokine receptor CXCR4 to beta-2 integrin LFA-1 in hematopoietic precursors. This kinase is involved in the induction of stress-activated protein kinase (SAPK), but not ERK or p38 MAPK, in response to genotoxic agents. In a word, Lyn kinase functions primarily as a negative regulator, but can also function as an activator, depending on the context. Tyrosine-protein kinase Lyn is Required for the initiation of the B-cell response, but also its down-regulation and termination. It also plays an important role in the regulation of B-cell differentiation, proliferation, survival, and apoptosis, and is important for immune self-tolerance. It has been reported that Lyn kinase plays a role in the inflammatory response to bacterial lipopolysaccharide. Lyn kinase Mediates the responses to cytokines and growth factors in hematopoietic progenitors, platelets, erythrocytes, and in mature myeloid cells, such as dendritic cells, neutrophils, and eosinophils.
存储条件Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字JTK-8 | JTK 8
关键字: p56Lyn;p53Lyn;LYN proto-oncogene, Src family tyrosine kinase;JTK8;TargetMol

公司简介

成立日期 2013-04-18 (14年) 注册资本 589.8595万人民币
员工人数 100-500人 年营业额 ¥ 1亿以上
主营行业 天然产物,生物化工,化学试剂,生物技术服务 经营模式 贸易,工厂,试剂,定制,服务
  • TargetMol 中国(陶术生物)
VIP 1年
  • 公司成立:14年
  • 注册资本:589.8595万人民币
  • 企业类型:股份有限公司(非上市、自然人投资或控股)
  • 主营产品:活性分子、生化试剂、天然产物、重组蛋白、抗体相关、试剂盒、药物筛选化合物库、技术服务
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