STAT6, Human, 重组蛋白 (His)|TMPY-02603|TargetMol

价格	￥428
包装	5μg

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中文名称:STAT6, Human, 重组蛋白 (His)	英文名称:STAT6 Protein, Human, Recombinant (His)
品牌: TargetMol	产地: 美国
保存条件: Lyophilized powder: -20~-80°C for 1 year \| Solution: -80°C for 6 months	纯度规格: 91.10%
产品类别: 抑制剂
货号: TMPY-02603

名称	STAT6 Protein, Human, Recombinant (His)
描述	Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6 plays a central role in exerting interleukin-4 (IL-4) mediated biological responses and is found to induce the expression of BCL2L1/BCL-XL, which is responsible for the anti-apoptotic activity of IL4. Transcriptional activation by STAT6 requires the interaction with coactivators like p300 and the CREB-binding protein (CBP). NF-κB and tyrosine-phosphorylated Stat6 can directly bind each other in vitro and in vivo, which suggests that the direct interaction between Stat6 and NF-κB may provide a basis for synergistic activation of transcription by IL-4 and activators of NF-κB.
存储条件	Lyophilized powder: -20~-80°C for 1 year \| Solution: -80°C for 6 months
关键字	D12S-1644 \| D12S 1644

关键字： STAT6C|||STAT6B|||signal transducer and activator of transcription 6, interleukin-4 induced|||IL-4-STAT|||D12S1644|TargetMol

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