BMP5, Human, 重组蛋白 (hFc),BMP-5 Protein, Human, Recombinant (hFc)
  • BMP5, Human, 重组蛋白 (hFc),BMP-5 Protein, Human, Recombinant (hFc)

BMP5, Human, 重组蛋白 (hFc)|TMPY-00681|TargetMol

价格 1350
包装 20μg
最小起订量 20μg
发货地 上海
更新日期 2026-05-08
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产品详情

中文名称:BMP5, Human, 重组蛋白 (hFc)英文名称:BMP-5 Protein, Human, Recombinant (hFc)
品牌: TargetMol产地: 美国
保存条件: Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months产品类别: 抑制剂
种属: Human表达系统: HEK293 Cells
蛋白长度: A DNA sequence encoding the carboxy-terminal domain (Gln 324-His 454) (the mature chain) of human BMP5 (NP_066551.1) was expressed with the fused Fc region of human IgG1 at the N-terminus. Predicted N terminal: Glu 20标签: N-hFc
货号: T011|TMPY-00681
2026-05-08 BMP5, Human, 重组蛋白 (hFc) BMP-5 Protein, Human, Recombinant (hFc) 20μg/1350RMB 1350 TargetMol 美国 Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months 抑制剂

Product Introduction

Bioactivity

名称BMP-5 Protein, Human, Recombinant (hFc)
描述Bone Morphogenetic Protein 5 (BMP-5) is a member of the structurally and functionally related bone morphogenetic proteins (BMPs) which constitute a novel subfamily of the transforming growth factor β (TGF-β) superfamily. In agreement with a possible role in the control of cell death, BMP-5 exhibited a regulated pattern of expression in the interdigital tissue. Transcripts of BMP-5 and BMP-5 protein were abundant within the cytoplasm of the fragmenting apoptotic interdigital cells in a way suggesting that delivery of BMPs into the tissue is potentiated during apoptosis. Gain-of-function experiments demonstrated that BMP-5 has the same effect as other interdigital BMPs inducing apoptosis in the undifferentiated mesoderm and growth in the prechondrogenic mesenchyme. BMP-5 is a member of the 60A subgroup of BMPs, other members of which have been shown to stimulate dendritic growth in central and peripheral neurons. The signaling pathway that mediates the dendrite-promoting activity of BMP-5 may involve binding to BMPR-IA and activation of Smad-1, and relative levels of BMP antagonists such as noggin and follistatin may modulate BMP-5 signaling. Since BMP-5 is expressed at relatively high levels not only in the developing but also the adult nervous system, these findings suggest the possibility that BMP-5 regulates dendritic morphology not only in the developing but also the adult nervous system. BMP-5 may play important roles not only in myocardial differentiation but also in the formation and maintenance of endocardial cushion tissue. Additionally, a high expression level of BMP-5 has been detected in certain tumors of mesenchymal origin.
存储条件Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字: bone morphogenetic protein 5;TargetMol

公司简介

成立日期 2013-04-18 (14年) 注册资本 589.8595万人民币
员工人数 100-500人 年营业额 ¥ 1亿以上
主营行业 天然产物,生物化工,化学试剂,生物技术服务 经营模式 贸易,工厂,试剂,定制,服务
  • TargetMol 中国(陶术生物)
VIP 1年
  • 公司成立:14年
  • 注册资本:589.8595万人民币
  • 企业类型:股份有限公司(非上市、自然人投资或控股)
  • 主营产品:活性分子、生化试剂、天然产物、重组蛋白、抗体相关、试剂盒、药物筛选化合物库、技术服务
  • 公司地址:静安区江场三路238号8楼
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