SFRP2, Mouse, 重组蛋白 (His),SFRP2 Protein, Mouse, Recombinant (His)
  • SFRP2, Mouse, 重组蛋白 (His),SFRP2 Protein, Mouse, Recombinant (His)

SFRP2, Mouse, 重组蛋白 (His)|TMPY-00920|TargetMol

价格 683
包装 5μg
最小起订量 5μg
发货地 上海
更新日期 2026-05-08
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产品详情

中文名称:SFRP2, Mouse, 重组蛋白 (His)英文名称:SFRP2 Protein, Mouse, Recombinant (His)
品牌: TargetMol产地: 美国
保存条件: Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months产品类别: 抑制剂
种属: Mouse表达系统: HEK293 Cells
蛋白长度: A DNA sequence encoding the mouse sFRP2 (NP_033170.1) (Met 1-Cys 295) was expressed with a C-terminal polyhistidine tag. Predicted N terminal: Leu 25标签: C-His
货号: T011|TMPY-00920
2026-05-08 SFRP2, Mouse, 重组蛋白 (His) SFRP2 Protein, Mouse, Recombinant (His) 5μg/683RMB 683 TargetMol 美国 Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months 抑制剂

Product Introduction

Bioactivity

名称SFRP2 Protein, Mouse, Recombinant (His)
描述The Secreted frizzled-related protein (SFRP) family consists of five secreted glycoproteins in humans (SFRP1~5) that act as extracellular signaling ligands. Each SFRP is approximately 3 amino acids in length and contains a cysteine-rich domain (CRD) that shares 3-5% sequence homology with the CRD of Frizzled (Fz) receptors, a putative signal sequence, and a conserved hydrophilic carboxy-terminal domain. SFRPs are able to bind Wnt proteins and Fz receptors in the extracellular compartment. The interaction between SFRPs and Wnt proteins prevents the latter from binding the Fz receptors. The Wnt pathway plays a key role in embryonic development, cell differentiation and cell proliferation. sFRP2 is a member of the SFRP family acting as soluble modulators of Wnt signaling and contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins called FZ domain and a NTR domain.sFRP2 inhibites hypoxia induced endothelial cell apoptosis and increases endothelial cell migration. It prevents mesoderm specification and maintains the cells in the undifferentiated state. SFRP2 is also a novel stimulator of angiogenesis that stimulates angiogenesis via a calcineurin/NFAT pathway, thus is regarded as a favorable target for the inhibition of angiogenesis in solid tumors. Mouse sFRP2 is highly expressed in the eye and is also detected in heart and lung at low level.
存储条件Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months
关键字AI-851596 | AI 851596
关键字: secreted frizzled-related protein 2;Sdf5;AI851596;TargetMol

公司简介

成立日期 2013-04-18 (14年) 注册资本 589.8595万人民币
员工人数 100-500人 年营业额 ¥ 1亿以上
主营行业 天然产物,生物化工,化学试剂,生物技术服务 经营模式 贸易,工厂,试剂,定制,服务
  • TargetMol 中国(陶术生物)
VIP 1年
  • 公司成立:14年
  • 注册资本:589.8595万人民币
  • 企业类型:股份有限公司(非上市、自然人投资或控股)
  • 主营产品:活性分子、生化试剂、天然产物、重组蛋白、抗体相关、试剂盒、药物筛选化合物库、技术服务
  • 公司地址:静安区江场三路238号8楼
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