IL-15RA&IL-15, Human, 重组蛋白 - PBS Lyophilized (hFc),IL-15RA & IL-15 Protein, Human, Recombinant - PBS Lyophilized (hFc)

IL-15RA&IL-15, Human, 重组蛋白 - PBS Lyophilized (hFc)|TMPJ-01462|TargetMol

价格	￥1320
包装	20μg

最小起订量	20μg
发货地	上海
更新日期	2026-05-08

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产品详情

中文名称:IL-15RA&IL-15, Human, 重组蛋白 - PBS Lyophilized (hFc)	英文名称:IL-15RA & IL-15 Protein, Human, Recombinant - PBS Lyophilized (hFc)
品牌: TargetMol	产地: 美国
保存条件: Lyophilized powder: -20~-80°C for 1 year \| Solution: -80°C for 6 months	纯度规格: 98.00%
产品类别: 抑制剂
种属: Human	表达系统: HEK293 Cells
蛋白长度: Ile31-Asp96&Asn49-Ser162 (Asn120Asp)	标签: C-hFc
货号: T011\|TMPJ-01462

Product Introduction

Bioactivity

名称	IL-15RA & IL-15 Protein, Human, Recombinant - PBS Lyophilized (hFc)
描述	IL15RA is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells.IL-15 is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 binds to the alpha subunit of the IL-15RA with high affinity. IL-15 also binds to the beta and gamma chains of the IL-2 receptor, but not the alpha subunit of the IL2 receptor. IL-15 is structurally and functionally related to IL-2. Both cytokines share some subunits of receptors, allowing them to compete for and negatively regulate each other's activity. The number of CD8+ memory T cells is controlled by a balance between IL-15 and IL-2. Despite their many overlapping functional properties, IL-2 and IL-15 are, in fact, quite distinct players in the immune system. IL-15 is constitutively expressed by a wide variety of cell types and tissues, including monocytes, macrophages and DCs. The enhanced activity of the IL-15N72D:IL-15RαSu/Fc complex is likely the result of the increased binding activity of IL-15N72D to IL-15Rβγ c , optimized cytokine trans-presentation by the IL-15RαSu domain, the dimeric nature of the cytokine domain and its increased in vivo half-life compared to IL-15. These findings indicate that this IL-15 superagonist complex could serve as a superior immunostimulatory therapeutic agent.
存储条件	Lyophilized powder: -20~-80°C for 1 year \| Solution: -80°C for 6 months
关键字	IL-15 Receptor a & IL-15 Fusion Protein \| IL 15

关键字： Interleukin-15;IL15RA&IL15 Complex;IL15RA&IL15;IL-15 Receptor α & IL-15 Fusion Protein;IL-15 Receptor alpha & IL-15 Fusion Protein;IL-15;IL15;TargetMol

公司简介

成立日期	2013-04-18 （14年）	注册资本	589.8595万人民币
员工人数	100-500人	年营业额	￥ 1亿以上
主营行业	天然产物,生物化工,化学试剂,生物技术服务	经营模式	贸易,工厂,试剂,定制,服务

TargetMol 中国（陶术生物）

VIP 1年

公司成立：14年
注册资本：589.8595万人民币
企业类型：股份有限公司(非上市、自然人投资或控股)
主营产品：活性分子、生化试剂、天然产物、重组蛋白、抗体相关、试剂盒、药物筛选化合物库、技术服务
公司地址：静安区江场三路238号8楼

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