Cathepsin C, Human, 重组蛋白 (His)|TMPY-00732|TargetMol

价格	￥1130
包装	10μg

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中文名称:Cathepsin C, Human, 重组蛋白 (His)	英文名称:Cathepsin C Protein, Human, Recombinant (His)
品牌: TargetMol	产地: 美国
保存条件: Lyophilized powder: -20~-80°C for 1 year \| Solution: -80°C for 6 months	产品类别: 抑制剂
种属: Human	表达系统: HEK293 Cells
蛋白长度: A DNA sequence encoding the pro form of human cathepsin C (NP_001805.3) (Met 1-Leu 463) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Asp 25	标签: C-His
货号: T011\|TMPY-00732

名称	Cathepsin C Protein, Human, Recombinant (His)
描述	Cathepsins are proteases found in many types of cells conserved in all animals, which have a vital role in mammalian cellular turnover such as bone resorption. The lysosomal cysteine protease Cathepsin C (CTSC), also known as dipeptidyl peptidase I (DPPI/DPP1), activates a number of granule-associated serine proteases with pro-inflammatory and immune functions by removal of their inhibitory N-terminal dipeptides. This lysosomal exo-cysteine protease belonging to the peptidase C1 family. Active cathepsin C is found in lysosomes as a 200-kDa multimeric enzyme. Subunits constituting this assembly all arise from the proteolytic cleavage of a single precursor giving rise to three peptides: the propeptide, the alpha- and the beta-chains. It is a central coordinator for activation of many serine proteases in immune/inflammatory cells. Defects in the Cathepsin C have been shown to be a cause of Papillon-Lefevre disease, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Cathepsin C plays a key role in the activation of several degradative enzymes linked to tissue destruction in inflammatory diseases. Thus, it is a therapeutic target for the treatment of a number of inflammatory and autoimmune diseases.
存储条件	Lyophilized powder: -20~-80°C for 1 year \| Solution: -80°C for 6 months
关键字	PDON-1 \| PDON 1 \| DPP-1 \| DPP 1

关键字： PLS;PDON1;PALS;JPD;JP;HMS;DPP-I;DPPI;DPP1;CPPI;cathepsin C;TargetMol

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产品名称	价格		公司名称	报价日期
重组Human DSG1 蛋白, C-His	￥1588	VIP2年	普健生物（武汉）科技有限公司	2026-05-15
重组人Cathepsin C蛋白, His Tag (MALS verified)	询价	VIP3年	北京百普赛斯生物科技股份有限公司	2026-05-12
蛋白C(PROC)重组蛋白	￥3000	VIP7年	上海泽叶生物科技有限公司	2026-05-15

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