C-ABL/ABL1, Human, 重组蛋白 (GST),C-ABL/ABL1 Protein, Human, Recombinant (GST)

C-ABL/ABL1, Human, 重组蛋白 (GST)|TMPY-04396|TargetMol

价格	￥5270
包装	100μg

最小起订量	100μg
发货地	上海
更新日期	2026-05-08

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产品详情

中文名称:C-ABL/ABL1, Human, 重组蛋白 (GST)	英文名称:C-ABL/ABL1 Protein, Human, Recombinant (GST)
品牌: TargetMol	产地: 美国
保存条件: Store at low temperature Store at -80°C	纯度规格: 90.90%
产品类别: 抑制剂
种属: Human	表达系统: Baculovirus Insect Cells
蛋白长度: A DNA sequence encoding the amino acid sequence (Pro 137-Ser 554) of human ABL1 isoform B (NP_009297.2) was fused with the GST tag at the N-terminus. Predicted N terminal: Met	标签: N-GST
货号: T011\|TMPY-04396

Product Introduction

Bioactivity

名称	C-ABL/ABL1 Protein, Human, Recombinant (GST)
描述	c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cytosol, and c-Abl is present in the nucleus as well. c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-beta-induced toxicity and tau phosphorylation. c-Abl has been implicated in many cellular processes including differentiation, division, adhesion, death, and stress response. c-Abl is a latent tyrosine kinase that becomes activated in response to numerous extra- and intra-cellular stimuli. The c-Abl protein is a ubiquitously expressed nonreceptor tyrosine kinase involved in the development and function of many mammalian organ systems, including the immune system and bone. It regulates the cellular response to TAM through functional interaction with the estrogen receptor, which suggests c-Abl as a therapeutic target and a prognostic tumor marker for breast cancer. c-Abl also plays a key role in signaling chemokine-induced T-cell migration. In addition, c-Abl contains NLSs (nuclear localization signals) and DNA-binding sequences important for nuclear functions. c-Abl has become an important therapeutic target in human chronic myeloid leukaemia.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
存储条件	Store at low temperature Store at -80°C
关键字	JTK-7 \| JTK 7

关键字： v-abl;p150;JTK7;c-ABL1;c-ABL;bcr/abl;ABL proto-oncogene 1, non-receptor tyrosine kinase;ABL;TargetMol

公司简介

成立日期	2013-04-18 （14年）	注册资本	589.8595万人民币
员工人数	100-500人	年营业额	￥ 1亿以上
主营行业	天然产物,生物化工,化学试剂,生物技术服务	经营模式	贸易,工厂,试剂,定制,服务

TargetMol 中国（陶术生物）

VIP 1年

公司成立：14年
注册资本：589.8595万人民币
企业类型：股份有限公司(非上市、自然人投资或控股)
主营产品：活性分子、生化试剂、天然产物、重组蛋白、抗体相关、试剂盒、药物筛选化合物库、技术服务
公司地址：静安区江场三路238号8楼

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C-ABL/ABL1, Human, 重组蛋白 (GST)|TMPY-04396|TargetMol相关厂家报价

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重组Human B2M 蛋白, C-His	￥1788	VIP2年	普健生物（武汉）科技有限公司	2026-05-19
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