WWP2, Human, 重组蛋白 (His & GST)|TMPY-02950|TargetMol

价格	￥495
包装	5μg

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中文名称:WWP2, Human, 重组蛋白 (His & GST)	英文名称:WWP2 Protein, Human, Recombinant (His & GST)
品牌: TargetMol	产地: 美国
保存条件: Lyophilized powder: -20~-80°C for 1 year \| Solution: -80°C for 6 months	产品类别: 抑制剂
种属: Human	表达系统: Baculovirus Insect Cells
蛋白长度: A DNA sequence encoding the human WWP2 (O00308) (Met1-Glu870) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus. Predicted N terminal: Met	标签: His, GST
货号: T011\|TMPY-02950

名称	WWP2 Protein, Human, Recombinant (His & GST)
描述	WWP2 contains 1 C2 domain, 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain and 4 WW domains. It is an E3 ubiquitin-protein ligase that accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. WWP2 can be detected in heart, throughout the brain, placenta, lung, liver, muscle, kidney and pancreas. It is also expressed in spleen and peripheral blood leukocytes. WWP2 polyubiquitinates POU5F1 by 'Lys-63'-linked conjugation and promotes it to proteasomal degradation; in embryonic stem cells (ESCs) the ubiquitination is proposed to regulate POU5F1 protein level. WWP2 ubiquitinates EGR2 and promotes it to proteasomal degradation; in T-cells the ubiquitination inhibits activation-induced cell death. It also ubiquitinates SLC11A2; the ubiquitination is enhanced by presence of NDFIP1 and NDFIP2. WWP2 ubiquitinates RPB1 and promotes it to proteasomal degradation.
存储条件	Lyophilized powder: -20~-80°C for 1 year \| Solution: -80°C for 6 months
关键字	AIP-2 \| AIP 2

关键字： WWp2-like;WW domain containing E3 ubiquitin protein ligase 2;AIP2;TargetMol

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产品名称	价格		公司名称	报价日期
Recombinant Human WWP2 Protein (His & GST tag)	￥1950	VIP4年	上海沪震实业有限公司	2026-05-18
重组Human DSG3 蛋白, C-His	￥1588	VIP2年	普健生物（武汉）科技有限公司	2026-05-18
GST重组蛋白纯化试剂	￥1000		生工生物工程（上海）股份有限公司	2026-05-07

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