TNF beta, Human, 重组蛋白|TMPY-02153|TargetMol

价格	￥389
包装	5μg

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中文名称:TNF beta, Human, 重组蛋白	英文名称:TNF beta Protein, Human, Recombinant
品牌: TargetMol	产地: 美国
保存条件: Lyophilized powder: -20~-80°C for 1 year \| Solution: -80°C for 6 months	纯度规格: 94.80%
产品类别: 抑制剂
种属: Human	表达系统: E. coli
蛋白长度: A DNA sequence encoding the mature form of human TNFβ (P01374) (Leu 35-Leu 205) was expressed and purified, with an initial Met at the N-terminus. Predicted N terminal: Met	标签: Tag Free
货号: T011\|TMPY-02153

名称	TNF beta Protein, Human, Recombinant
描述	Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs to the tumor necrosis factor family. TNF-beta/TNFSF1/Lymphotoxin alpha is highly inducible, secreted, and exists as a homotrimeric molecule. It is a cytokine that in its homotrimeric form binds to TNFRSF1A / TNFR1, TNFRSF1B / TNFBR, and TNFRSF14 / HVEM. In its heterotrimeric form with LTB, TNF-beta/TNFSF1/Lymphotoxin alpha binds to TNFRSF3 / LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells. TNF-beta/TNFSF1/Lymphotoxin alpha forms heterotrimers with lymphotoxin-beta which anchors lymphotoxin-alpha to the cell surface. It mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. TNF-beta/TNFSF1/Lymphotoxin alpha is also involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in TNF-beta/TNFSF1/Lymphotoxin alpha are a cause of susceptibility psoriatic arthritis which is an inflammatory, seronegative arthritis associated with psoriasis. It is a heterogeneous disorder ranging from a mild, non-destructive disease to a severe, progressive, erosive arthropathy.
存储条件	Lyophilized powder: -20~-80°C for 1 year \| Solution: -80°C for 6 months
关键字	TNFSF-1 \| TNFSF 1

关键字：肿瘤坏死因子;TNFSF1;TNFB;TNF β;lymphotoxin α;lymphotoxin alpha;LT;TargetMol

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