Product Name： SPACE peptide
CAS No.：1621717-95-0
Synonyms：皮肤穿透肽SPACE peptide
Catalog No.：218P861
Brand：Typeptide Biotech（肽研生物）
Description：SPACE peptide是一种皮肤穿透肽，是由11个氨基酸组成的环状多肽。SPACE peptide 能增强大分子透明质酸的局部传递。SPACE 肽与小分子和蛋白质等货物结合时，能够促进它们穿过角质层进入表皮和真皮.SPACE 肽还表现出对各种细胞的渗透增加，包括角质形成细胞、成纤维细胞和内皮细胞，可能是通过巨胞饮作用途径.SPACE 肽通过跨细胞途径增强环孢菌素 A 皮肤渗透，通过 SPACE 与角蛋白和环孢菌素 A 的同时结合增强其分配到富含角蛋白的角质细胞中.
SPACE peptide is a skin-penetrating peptide composed of 11 amino acids in a cyclic polypeptide form. It enhances the local delivery of large molecular weight hyaluronic acid. When binding to cargoes such as small molecules and proteins, SPACE peptide facilitates their penetration through the stratum corneum into the epidermis and dermis. Additionally, SPACE peptide demonstrates increased permeability to various cell types, including keratinocytes, fibroblasts, and endothelial cells, likely via macropinocytosis. Through a transcellular pathway, SPACE peptide enhances the skin penetration of cyclosporine A, and its co-delivery with keratin and cyclosporine A increases its distribution into keratin-rich keratinocytes
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | ACTGSTQHQCG(Disulfide bridge:Cys2-Cys10) |
Sequence(3-letter code) | H-Ala-Cys-Thr-Gly-Ser-Thr-Gln-His-Gln-Cys-Gly-OH(Disulfide bridge：Cys2-Cys10) |
Peptide Structure | 
|
Molecular Formula | C40H63N15O17S2 |
Molecular Weight | 1090.15 |
订购联系方式：
南京肽研生物生物科技有限公司
手机号：19961912513(微信同号)
QQ: 2178255659
邮箱：sales@typeptide.com
联系人：顾经理
申明：本产品仅供科研使用，不得用于人体。
关键字： SPACE peptide;皮肤穿透肽SPACE peptide;1621717-95-0;多肽;多肽合成;
肽研生物坐落于国家级新区南京江北新区新材料产业园，是一家专业从事多肽产 品的研发、生产和销售以及多肽技术转让的高新技术企业。公司秉持“诚信、严 谨、务实”的匠人精神，持续投入研发，不断创新，致力于为科研工作者提供丰 富全面的多肽修饰类型和优质的产品。