Product Name:C3bot (154-182)
CAS No.:1246280-79-4
Synonyms:梭菌C3蛋白(154-182)
Catalog No.:218P166
Brand:Typeptide Biotech(肽研生物)
Description:C3bot (154-182)是梭菌C3蛋白的转移酶缺陷型神经营养多肽片段,是由29个氨基酸组成的直链多肽。C3bot (154-182)在亚微摩尔浓度下促进海马神经元的轴突和树突生长和分支,还促进器官型海马/内嗅切片培养物中靶组织的神经再生,可以通过非酶机制降低活性神经元 RhoA 的水平,具备增强脊髓损伤小鼠模型的功能恢复和再生的生活学功能。
C3bot (154-182) is a transferase deficient neurotrophin fragment of Clostridium C3 protein, consisting of a straight chain peptide of 29 amino acids. C3bot (154-182) promotes axonal and dendritic growth and branching of hippocampal neurons at sub micromolar concentrations, as well as neural regeneration of target tissues in organotypic hippocampal/olfactory slice cultures. It can reduce the level of RhoA in active neurons through non enzymatic mechanisms and has a life science function of enhancing functional recovery and regeneration in spinal cord injury mouse models.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | VAKGSKAGYIDPISAFAGQLEMLLPRHST |
Sequence(3-letter code) | H-Val-Ala-Lys-Gly-Ser-Lys-Ala-Gly-Tyr-Ile-Asp-Pro-Ile-Ser-Ala-Phe-Ala-Gly-Gln-Leu-Glu-Met-Leu-Leu-Pro-Arg-His-Ser-Thr-OH |
Peptide Structure | 
|
Molecular Formula | C137H221N37O40S1 |
Molecular Weight | 3058.55 |
订购联系方式:
南京肽研生物生物科技有限公司
手机号:19961912513(微信同号)
QQ: 2178255659
邮箱:sales@typeptide.com
联系人:顾经理
申明:本产品仅供科研使用,不得用于人体。
关键字: C3bot (154-182);梭菌C3蛋白(154-182);1246280-79-4;多肽;多肽合成;
肽研生物坐落于国家级新区南京江北新区新材料产业园,是一家专业从事多肽产 品的研发、生产和销售以及多肽技术转让的高新技术企业。公司秉持“诚信、严 谨、务实”的匠人精神,持续投入研发,不断创新,致力于为科研工作者提供丰 富全面的多肽修饰类型和优质的产品。