巯基硅胶金属吸附剂 除钯试剂 原料除钯吸附剂主打

巯基硅胶除钯吸附剂是以高比表面积多孔硅胶为载体，通过稳定化学键合技术接枝高密度巯基（-SH）官能团的功能化吸附材料。依托巯基与钯离子（Pd²⁺、Pd⁰）的强配位络合作用，可快速、高选择性地深度捕集体系中各类形态钯杂质，包括游离钯离子、胶体钯、钯碳微粒及钯 - 膦络合物。产品机械强度高、耐酸碱、不溶胀、无官能团溶出，兼容甲醇、乙醇、四氢呋喃等常用制药溶剂，适配常温常压操作。可将原料药、中间体中钯残留从数百 ppm 稳定降至 1ppm 以下，满足药典严苛标准，广泛用于 Suzuki、Heck 等钯催化反应后处理，兼具贵金属回收价值，符合 GMP 规范。

Thiol-Functionalized Silica Gel for Palladium ScavengingThiol-functionalized silica gel is a high-performance adsorbent material, which is prepared by chemically bonding high-density thiol (-SH) groups onto the surface of porous silica gel with large specific surface area. Relying on the strong coordination and complexation between thiol groups and palladium species (Pd²⁺, Pd⁰), it can rapidly and highly selectively capture various forms of palladium impurities in the system, including free palladium ions, colloidal palladium, palladium on carbon particles, and palladium-phosphine complexes. This product features high mechanical strength, acid and alkali resistance, non-swelling property, and no functional group leaching. It is compatible with common pharmaceutical solvents such as methanol, ethanol, and tetrahydrofuran, and can operate under ambient temperature and pressure. It can stably reduce palladium residues in APIs and intermediates from hundreds of ppm to below 1 ppm, meeting strict pharmacopoeia standards. Widely used in post-treatment of palladium-catalyzed reactions such as Suzuki and Heck couplings, it also has the value of precious metal recovery and complies with GMP regulations。