吉非替尼

熔点

119-1200C

沸点

586.8±50.0 °C(Predicted)

密度

1.322±0.06 g/cm3(Predicted)

储存条件

room temp

溶解度

Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 4 mg/ml).

形态

powder

酸度系数(pKa)

7.00±0.10(Predicted)

颜色

white to beige

稳定性

Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.

InChI

InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)

InChIKey

XGALLCVXEZPNRQ-UHFFFAOYSA-N

SMILES

N1=C2C(C=C(OCCCN3CCOCC3)C(OC)=C2)=C(NC2=CC=C(F)C(Cl)=C2)N=C1

CAS 数据库

184475-35-2(CAS DataBase Reference)

危险性符号(GHS)

GHS07

警示词

Warning

危险性描述

H302-H315-H319-H335

防范说明

P301+P312+P330-P305+P351+P338

安全说明

24/25

WGK Germany

WGK 3

海关编码

29349990

存储类别

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

危险性类别

Acute Tox. 4 Oral
Aquatic Chronic 1
Carc. 2
Eye Dam. 1
Repr. 1B
Skin Irrit. 2
STOT RE 2 Oral