(Muzastotug)Biosimilar Reference Antibody-GS40452 新品

货号：GS40452

Muzastotug is a humanized IgG1‑kappa monoclonal antibody developed by Adagene as an immune stimulant and anti‑tumor agent. It functions as a CTLA‑4 inhibitor by specifically binding to and blocking the cytotoxic T‑lymphocyte‑associated protein 4 (CTLA‑4) immune checkpoint receptor. Unlike some earlier anti‑CTLA‑4 antibodies, muzastotug is designed to preferentially target and modulate regulatory T cells (Tregs) within the tumor microenvironment, aiming to deplete or inhibit their immunosuppressive activity while preserving or enhancing effector T‑cell function.