Monoclonal Anti-Doxorubicin specific Antibody, Rabbit IgG (1M2B1)
特异性(Specificity)
Specifically recognizes Doxorubicin.
抗体来源(Source)
Monoclonal Anti-Doxorubicin specific Antibody, Rabbit IgG (1M2B1) is a Rabbit monoclonal antibody recombinantly expressed from HEK293 cells.
克隆号(Clone)
1M2B1
亚型(Isotype)
Rabbit IgG | Rabbit Kappa
偶联(Conjugate)
Unconjugated
免疫原(Immunogen)
Doxorubicin-BSA
应用(Application)
Application | Recommended Usage |
ELISA | 0.06-125 ng/mL |
纯化(Purification)
Protein A purified / Protein G purified
制剂(Formulation)
Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.
Please contact us for customized product forms or formulations.
重构方法(Reconstitution)
Please refer to the Certificate of Analysis (CoA) for specific instructions.
For best performance, we strongly recommend following the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored in a lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.

背景介绍
多柔比星(Doxorubicin)是一种具有细胞毒性的蒽环类抗生素,也是一种抗癌化疗药物。作为ADC药物的有效载荷,多柔比星能直接作用于DNA,插入DNA双螺旋链之间,导致DNA解旋,改变DNA的模板特性,并抑制DNA聚合酶,从而抑制DNA和RNA的合成。抗多柔比星抗体是一种兔单克隆抗体,能特异性识别多柔比星,而不与其他有效载荷反应,其灵敏度高于小鼠抗体。该抗多柔比星抗体是药代动力学(PK)检测中用于测定偶联抗体的一种有用试剂。
关键字: Doxorubicin抗体;Doxorubicin;Anti-Doxorubicin;百普赛斯;ACRO;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。