Monoclonal Anti-Mumps virus Fusion glycoprotein F0 Antibody, Human IgG1 (8F8) (MALS verified)
抗体来源(Source)
Monoclonal Anti-Mumps virus Fusion glycoprotein F0 Antibody, Human IgG1 (8F8) is a chimeric monoclonal antibody recombinantly expressed from HEK293, which combines the variable region of a mouse monoclonal antibody with Human constant domain.
克隆号(Clone)
F8
种属(Species)
Mouse
亚型(Isotype)
Human IgG1 | Human Kappa
偶联(Conjugate)
Unconjugated
抗体类型(Antibody Type)
Recombinant Monoclonal
种属反应性(Reactivity)
Mumps virus (strain Miyahara vaccine) (MuV)
免疫原(Immunogen)
Recombinant Mumps virus (strain Miyahara vaccine) (MuV) Fusion glycoprotein F0 is expressed from human 293 cells
特异性(Specificity)
Specifically recognizes Mumps virus Fusion glycoprotein F0 Protein.
应用(Application)
Application | Recommended Usage |
ELISA | 0.06-8 ng/mL |
纯度(Purity)
95% as determined by SDS-PAGE.
90% as determined by SEC-MALS.
纯化(Purification)
Protein A purified / Protein G purified
制剂(Formulation)
Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.
Please contact us for customized product forms or formulations.
重构方法(Reconstitution)
Please refer to the Certificate of Analysis (CoA) for specific instructions.
For best performance, we strongly recommend following the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored in a lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.

背景介绍
腮腺炎病毒的两种表面糖蛋白是血凝素-神经氨酸酶(HN)和融合蛋白(F)。这些糖蛋白对于病毒进入宿主细胞以及新生病毒粒子的传播至关重要。腮腺炎融合蛋白(F)是一种由538个氨基酸组成的I类融合表面糖蛋白,负责介导病毒与宿主细胞的膜融合。未切割的F蛋白含有三个疏水区:一个氨基端信号肽、F1的氨基端区域以及羧基端的跨膜结构域。该蛋白以前体分子(F0)形式合成,随后通过宿主内切蛋白酶(弗林蛋白酶)识别R-X-L/R-R基序而切割成具有活性的蛋白。F蛋白包含两个由二硫键连接的多肽链(F1和F2)。
关键字: Anti-RSV F;Fusion glycoprotein;Anti-Anti-RSV F;百普赛斯;ACRO;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。