货号:GS40643
Selicrelumab is a human monoclonal antibody agonist targeting CD40, a co-stimulatory receptor expressed on antigen-presenting cells (e.g., dendritic cells, B cells). By activating CD40 signaling, it enhances dendritic cell maturation, T cell priming, and anti-tumor immunity. It is being developed as an immunostimulatory agent for cancer immunotherapy, often in combination with chemotherapy or other immunotherapies.
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