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PKC nu, Human, 重组蛋白 (GST),PKC nu Protein, Human, Recombinant (GST)
  • PKC nu, Human, 重组蛋白 (GST),PKC nu Protein, Human, Recombinant (GST)

PKC nu, Human, 重组蛋白 (GST)|TMPY-04456|TargetMol

价格 ￥2530
包装 50μg
最小起订量 50μg
发货地 上海
更新日期 2026-05-11
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产品详情

中文名称:PKC nu, Human, 重组蛋白 (GST)英文名称:PKC nu Protein, Human, Recombinant (GST)
品牌: TargetMol产地: 美国
保存条件: Store at low temperature Store at -80°C产品类别: 抑制剂
种属: Human表达系统: Baculovirus Insect Cells
蛋白长度: A DNA sequence encoding the full length of human PRKD3 (NP_005804.1) (Met 1-Pro 890) was expressed with the GST tag at the N-terminus. Predicted N terminal: Met标签: N-GST
货号: T011|TMPY-04456
2026-05-11 PKC nu, Human, 重组蛋白 (GST) PKC nu Protein, Human, Recombinant (GST) 50μg/2530RMB 2530 TargetMol 美国 Store at low temperature Store at -80°C 抑制剂

Product Introduction

Bioactivity

名称PKC nu Protein, Human, Recombinant (GST)
描述Serine/threonine-protein kinase D3, also known as Protein kinase C nu type, Protein kinase EPK2, PRKD3, EPK2 and PRKCN, is a cytoplasm and membrane protein that belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and PKD subfamily. PRKD3 / PRKCN contains one PH domain, two phorbol-ester/DAG-type zinc fingers and one protein kinase domain. Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. They also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. PRKD3 / PRKCN converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. It is involved in resistance to oxidative stress. PRKD3 / PRKCN is activated by DAG and phorbol esters. Phorbol-ester/DAG-type domains 1 and 2 bind both DAG and phorbol ester with high affinity and mediate translocation to the cell membrane. Autophosphorylation of Ser-735 and phosphorylation of Ser-731 by PKC relieves auto-inhibition by the PH domain. PRKD3 / PRKCN can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. PRKD3 / PRKCN can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phospholipase C gamma and the involvement of other PKC family members.
存储条件Store at low temperature Store at -80°C
关键字PKD-3 | PKD 3 | EPK-2 | EPK 2
关键字： protein kinase D3;PRKCN;PKD3;PKC-NU;nPKC-NU;EPK2;TargetMol

公司简介

成立日期 2013-04-18 （14年） 注册资本 589.8595万人民币
员工人数 100-500人 年营业额 ￥ 1亿以上
主营行业 天然产物,生物化工,化学试剂,生物技术服务 经营模式 贸易,工厂,试剂,定制,服务
  • TargetMol 中国（陶术生物）
VIP 1年
  • 公司成立：14年
  • 注册资本：589.8595万人民币
  • 企业类型：股份有限公司(非上市、自然人投资或控股)
  • 主营产品：活性分子、生化试剂、天然产物、重组蛋白、抗体相关、试剂盒、药物筛选化合物库、技术服务
  • 公司地址：静安区江场三路238号8楼
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