Product Name：IRW
CAS No.：159718-10-2
Synonyms：三肽Ile-Arg-Trp-OH
Catalog No.：220P392
Brand：Typeptide Biotech（肽研生物）
Description：IRW 是一种从蛋清中提取的具有口服活性多肽，具有血管紧张素转换酶 (ACE) 抑制特性，是三个氨基酸组成的小分子多肽。IRW 可通过调节肝脏脂质代谢和增加线粒体含量，预防高脂饮食 (HFD) 诱导的非酒精性脂肪肝 (NAFLD)。IRW 能降低肝脏甘油三酯含量和脂滴大小。IRW 可增加肝脏线粒体复合物和柠檬酸合酶活性、5'-AMP 激活蛋白激酶的磷酸化以及微粒体甘油三酯转移蛋白的丰度。IRW 能增加磷酸化的乙酰辅酶 A 羧化酶 (acetyl CoA carboxylase) 和线粒体复合物，可用于炎症相关研究。
IRW is an orally active peptide extracted from egg white, with angiotensin-converting enzyme (ACE) inhibitory properties. It is a small molecule peptide composed of three amino acids. IRW can prevent non-alcoholic fatty liver disease (NAFLD) induced by high-fat diet (HFD) by regulating liver lipid metabolism and increasing mitochondrial content. IRW can reduce liver triglyceride content and lipid droplet size. IRW can increase liver mitochondrial complex and citrate synthase activity, phosphorylation of 5 '- AMP activated protein kinase, and abundance of microsomal triglyceride transfer protein. IRW can increase the phosphorylation of acetyl CoA carboxylase and mitochondrial complexes, which can be used in inflammation related research.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | IRW |
Sequence(3-letter code) | H-Ile-Arg-Trp-OH |
Peptide Structure | 
|
Molecular Formula | C23H35N7O4 |
Molecular Weight | 473.57 |
订购联系方式：
南京肽研生物生物科技有限公司
手机号：19961912513(微信同号)
QQ: 2178255659
邮箱：sales@typeptide.com
联系人：顾经理
申明：本产品仅供科研使用，不得用于人体。
关键字： IRW;三肽Ile-Arg-Trp-OH;159718-10-2;多肽;多肽合成;
肽研生物坐落于国家级新区南京江北新区新材料产业园，是一家专业从事多肽产 品的研发、生产和销售以及多肽技术转让的高新技术企业。公司秉持“诚信、严 谨、务实”的匠人精神，持续投入研发，不断创新，致力于为科研工作者提供丰 富全面的多肽修饰类型和优质的产品。