Ivermectin bulk active pharmaceutical ingredient (API) to the pharmaceutical industry. Our Ivermectin is manufactured by cGMP compliant facility. Welcome to contact us for further details including current DMF status for the product and up to date regulatory status of the manufacturing facility. We look forward to assisting you with your research and development projects.
What is Ivermectin?
Ivermectin (22, 23-dihydroavermectin B1a + 22,23-dihydroavermectin B1b) is a broad-spectrum antiparasitic avermectin medicine. It is sold under brand names Stromectol in the United States, Ivomec in Europe by Merial Animal Health, Mectizan in Canada by Merck and Ivexterm in Mexico by Valeant Pharmaceuticals International. While in development, it was assigned the code MK-933 by Merck.
What is the mechanism of action?
Ivermectin binds selectively and with high affinity to glutamate-gated chloride ion channels in invertebrate muscle and nerve cells of the microfilaria. This binding causes an increase in the permeability of the cell membrane to chloride ions and results in hyperpolarization of the cell, leading to paralysis and death of the parasite. Ivermectin also is believed to act as an agonist of the neurotransmitter gamma-aminobutyric acid (GABA), thereby disrupting GABA-mediated central nervous system (CNS) neurosynaptic transmission.
How to dose Ivermectin?
Take ivermectin tablets by mouth with a full glass of water. Do not take ivermectin with food. Follow the directions on the prescription label. As a general rule take ivermectin tablets 1 hour before breakfast. Do not take your medicine more often than directed.
What are the side effects?
- vision changes or problems with your vision;
- urinary or bowel problems;
- weakness, confusion, lack of coordination;
- eye redness, swelling, or pain; or
- seizure (convulsions).
Other less serious side effects may be more likely to occur, such as:
- nausea, diarrhea;
- dizziness;
- swelling of your hands, ankles, or feet;
- swelling or tenderness of your lymph nodes;
- itching or skin rash; or
- feeling that something is in your eye(s).
Storage
Store below 30 °C (86 °F).
关键字： Pharma Ingredient
Hebei Vistar Bio-Technology Co.Ltd is a professional enterprise specialized in R&D,production and trading of APIs(Active Pharmaceutical Ingredients);Intermediates;Veterinary products and Chemicals etc products.
Through many years effort,we have established strong relationship with many famous factories and companies worldwide.GMP,DMF etc files are available for you to register them in your Ministry of Health.And some of our products have already been registered in some countries.
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