| 产品编号 |
产品名称 |
产品包装 |
产品价格 |
| P5752-1mg |
Recombinant Human NT-pro-BNP |
1mg |
询价 |
|
Species
|
Gene ID
|
Accession
|
Source
|
Length
|
MW
|
Tag
|
|
Human
|
4879
|
P16860
|
E. coli
|
76aa
|
8.5kDa
|
－
|
|
About this Protein
|
|
Name
|
Recombinant Human NT-pro-BNP (Recombinant Human NT-pro-BNP; rHuNT-pro-BNP)；重组人血浆氨基末端脑利钠肽前体
|
|
Synonyms
|
BNP
|
|
Purity
|
>98% by SDS-PAGE and HPLC analyses.
|
|
Biological Activity
|
Data is not available.
|
|
Physical Appearance
|
Sterile Filtered White lyophilized (freeze-dried) powder.
|
|
Formulation
|
Lyophilized from a 0.2μm filtered concentrated solution in 20mM Tris-HCl, pH 8.0, 150mM NaCl.
|
|
Endotoxin
|
Less than 0.1EU/μg of rHuNT-pro-BNP as determined by LAL method.
|
|
Reconstitution
|
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.
|
|
Category
|
Cytokine
|
|
Background
|
Brain-type Natriuretic Peptide (BNP) is a nonglycosylated peptide that is produced predominantly by ventricular myocytes and belongs to the natriuretic peptide family. Proteolytic cleavage of the 12kDa BNP precursor gives rise to N-terminal Pro-BNP (NT-pro-BNP) and mature BNP. Plasma NT-proBNP is a marker for congestive heart failure, while mature BNP (aa 103-134) promotes vasodilation and fluid and sodium excretion. Human BNP precursor shares 29% and 51% aa sequence identity with mouse and porcine BNP precursor, respectively.
|
|
Amino Acid Sequence
|
HPLGSPGSAS DLETSGLQEQ RNHLQGKLSE LQVEQTSLEP LQESPRPTGV WKSREVATEG IRGHRKMVLY TLRAPR
|
包装清单:
|
产品编号
|
产品名称
|
包装
|
|
P5752-100μg
|
Recombinant Human NT-pro-BNP
|
100μg
|
|
P5752-500μg
|
Recombinant Human NT-pro-BNP
|
500μg
|
|
P5752-1mg
|
Recombinant Human NT-pro-BNP
|
1mg
|
|
-
|
说明书
|
1份
|
保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
为了您的安全和健康，请穿实验服并戴一次性手套操作。