Introduction:
Chinese name:N, N-Diethylnicotinamide(Nikethamide)
English name:N,N-Diethylnicotinamide(Nikethamide)
Molecular formula：C10H14N2O
Molecular weight:178.23
Melting point:23 °C(lit.)
Boiling point:296-300 °C(lit.)
Relative density:1.058-1.066（25/4℃）
Refractive index:n20/D 1.524(lit.)
Flash point:>230 °F
Shape:Liquid
pKa:pKa 3.46(H2O,t =20) (Uncertain)
Color:Clear colorless to yellow
CAS:59-26-7(CAS DataBase Reference)
EINECS：200-418-5
Related Categories:API;Small Molecular Inhibitors;Pharmaceutical API;NIKETHYL;-;Nitrogen cyclic compounds;Heterocyclic Compounds
Mol：59-26-7.mol
Purity: 99%
Indication:For central respiratory depression and respiratory depression caused by various reasons.It is a central stimulant and also used for intoxication of anesthetics and other central inhibitors.LD50 was 272 mg/kg by intraperitoneal injection in rats.
Adverse reactions:Common facial irritation, restlessness, convulsions, nausea and vomiting, etc.High doses can lead to elevated blood pressure, palpitations, sweating, facial flushing, vomiting, tremor, arrhythmia, convulsions, and even coma.
Taboo:Patients with hyperspasmia and convulsions.
Precautions:The action time is short and should be given at intervals depending on the condition.
Drug Interaction:Combined with other central stimulants, it has synergistic effect and can cause convulsions.
Packaging:25KG/Barrel
Note:Pharmaceutical Intermediates, Fine Chemicals, Chemical Reagents, Material Intermediates.
关键字： N, N-Diethylnicotinamide(Nikethamide)
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