CURIA的GEMAGIQUE™系列精细化工产品，包括GEMAGIQUE™ HP、GEMAGIQUE™ HPS、和GEMAGIQUE™ CP1，均为基于AMPS的合成高分子，主要应用于水基体系的凝固剂、水包油（O/W）乳化剂的增稠剂和稳定剂。这些复合物预先中和，易于使用，并为配方提供优异的屈服值和触感，即便在不添加主乳化剂的条件下，也能确保配方的卓越稳定性。
CURIA’s fine chemical products, the GEMAGIQUE™series, featuring GEMAGIQUE™HP, GEMAGIQUE™HPS, GEMAGIQUE™CP1, are synthetic polymers based on AMPS, crafted for application as rheology modifiers in aqueous systems, and as enhancers and thickeners for oil-in-water (O/W) emulsions. These compounds are pre-neutralized for ease of use and are designed to boost formulation by offering superior yield value and tactile experience, providing exceptional stability to formulations even in the absence of primary emulsifying agents.
应用 1: 乳液的创新制备
利用GEMAGIQUE™ HP 和 GEMAGIQUE™CP1，开创直接乳化与逆向乳化新纪元，实现水相向油相或油相向水相的无缝转换。这两种多功能成分适用于高达85°C的热工艺及冷工艺，打造0/W型乳液。采用直接加水搅拌的简化操作，免去了繁琐的中和步骤，即便在油相中也能轻松分散，无需担心聚合物早期水化引发的凝胶结团问题。制备的乳液不仅光泽度高，质地爽滑，还具有极佳的延展性和快速吸收特性，为轻盈且高雅的配方提供理想选择。
Application 1: Innovative Lotion Preparation
GEMAGIQUE™ HP and GEMAGIQUE™ CP1 redefine emulsification, enabling direct (oil into water) and reverse (water into oil) methods with ease. Suitable for both hot (up to 85°C) and cold processes, these multifunctional ingredients facilitate the creation of O/W emulsions. The simplicity of stirring directly into the water phase, avoiding the need for neutralization, and easy dispersion in the oil phase, even in the presence of emollients, streamlines lotion preparation. Emulsions crafted with GEMAGIQUE™ HP and GEMAGIQUE™ CP1 boast a glossy appearance, silky texture, excellent spreadability, and rapid absorption, making them ideal for light and sophisticated formulations.
应用 2: 无乳化剂的乳膏凝胶革新
GEMAGIQUE™ HP 和 GEMAGIQUE™ CP1能够在无需额外乳化剂的条件下，稳定不溶于水的液体如油，创造出0/W型配方的外观和质感。此技术开辟了一种无乳化剂乳霜凝胶的新时代，特别是对于寻求特殊流变特性和卓越皮肤相容性的现代配方而言。所得配方质感轻盈，奶霜般细腻，与传统增稠剂所制无乳化剂配方截然不同，稳定性得益于聚合物交联结构的独特设计，提供了稳定的屈服值，确保油滴或固体（如颜料）在水/聚合物基质中得到“捕获”。
Application 2: Emulsifier-free Cream Gel Innovation
GEMAGIQUE™ HP and GEMAGIQUE™ CP1 excel in stabilizing insoluble liquids, like oils, without additional emulsifiers, paving the way for O/W-like formulas and emulsifier-free cream gels. This opens the door to modern formulations with unique rheological properties and superior skin compatibility, offering a light, finely textured cream that contrasts sharply with the appearance of formulations using "traditional" thickeners. Their stabilizing effect is attributed to the unique crosslinked structure of the polymers, which provides a yield value capturing oil droplets or solids (e.g., pigments) within the water/polymer matrix, without compromising the formula's flow properties.
应用 3: 水性凝胶的创制艺术
通过GEMAGIQUE™ CP1精心调制的水性凝胶，透明度随所用GEMAGIQUE™ HP、GEMAGIQUE™ HPS和GEMAGIQUE™ CP1的量而变化。1%或更高浓度下，可实现更佳的透明效果，并通过添加如甘油的溶剂提高通透性。实践表明，使用无矿物质的去离子水可进一步提升凝胶的透明度，显示出与其他极性有机溶剂的优异兼容性，能制备含超50%乙醇的透明凝胶。此法不仅简便，还可溶解多种活性成分，省去了增溶剂的需求，使得包含芳香油、油溶性紫外线过滤剂、活性物质等成分的水醇凝胶易于制备。若乙醇或异丙醇含量适当，甚至可免去额外防腐剂，展现了制备水醇凝胶的最优流程与技巧。
Application 3: The Art of Water Gel Creation
The transparency of water gels created with GEMAGIQUE™ CP1 varies with the concentration of GEMAGIQUE™ HP, GEMAGIQUE™ HPS, and GEMAGIQUE™ CP1 used. Concentrations of 1% or higher yield more transparent gels, enhanced by adding solvents like glycerin for increased clarity. Practice has shown that using deionized water free of minerals can further improve gel transparency, with excellent compatibility with various polar organic solvents, allowing for the creation of transparent gels with over 50% ethanol content. Adding GEMAGIQUE™ ingredients to a water/ethanol mix dissolves active ingredients without the need for cosolvents, facilitating the preparation of water-alcohol gels containing essential oils, oil-soluble UV filters, actives, and film-forming agents. If the ethanol or isopropanol content is sufficient, additional preservatives may not be required, showcasing the optimal process for preparing water-alcohol gels with active solutions or film-formers.
产品特性
1) 多功能的粘度调节剂，适用于 O/W（油包水）和 W/O（水包油）乳液，提供灵活多变的配方选择。
2) 能与水及水溶性有机溶剂融合，形成均匀、清澈透明的凝胶，为产品带来优雅的质感。
3) 在 pH 3.5 至 9.0 范围内保持稳定，适应广泛的配方环境。
4) 提供卓越的使用体验：肌肤触感光滑、轻盈、清爽，无黏腻感。
5) 支持高达 20% 的油相含量，实现无乳化剂配方，简化产品成分。
6) 即用型产品，已预中和处理，使用便捷，简化生产流程。
7) 具有良好的耐紫外线性能，保护配方免受光照影响。
8) 支持冷配工艺，易于均质分散，提高生产效率。
9) 在超过 80% 的高酒精浓度下依然稳定，适用于高含醇配方。
Product Characteristics:
1) Multi-functional viscosity regulator suitable for O/W (oil-in-water) and W/O (water-in-oil) emulsions, offering versatile formulation options.
2) Able to blend with water and water-soluble organic solvents, forming uniform, clear, and transparent gels, imparting an elegant texture to the product.
3) Maintains stability within the pH range of 3.5 to 9.0, adaptable to a wide range of formulation environments.
4) Provides an exceptional user experience: smooth, lightweight, refreshing skin feel without any greasiness.
5) Supports oil phase content of up to 20%, enabling emulsifier-free formulations, simplifying product ingredients.
6) Ready-to-use product, pre-neutralized for convenient usage, simplifying the production process.
7) Exhibits excellent UV resistance, protecting formulations from light-induced degradation.
8) Supports cold processing technology, easy to homogenize and disperse, enhancing production efficiency.
9) Stable even at over 80% high alcohol concentration, suitable for high-alcohol formulations.
产品应用及添加量
1) 护肤系列（使用浓度0.3~0.7%）：包括滋养乳液、滋润面霜、紧致抗衰老凝胶、清新爽肤水；
2) 洁面与护理系列（使用浓度0.5~1%）：温和洁面凝胶、滋润洁面霜；
3) 发型造型系列：轻盈清爽发胶、定型发蜡；
4) 日常防护系列：全面防护防晒霜、轻盈防晒乳液、清透防晒凝胶；
5) 彩妆系列：自然透亮BB霜、遮瑕持久粉底；
6) 家庭必备系列（高酒精含量）：抗菌洗手凝胶。
Product Applications and Recommended Dosage:
1) Skincare series (concentration: 0.3~0.7%): including nourishing lotions, moisturizing creams, firming anti-aging gels, refreshing toners.
2) Cleansing and care series (concentration: 0.5~1%): gentle cleansing gels, moisturizing cleansing creams.
3) Hair styling series: lightweight styling gels, styling waxes.
4) Daily protection series: comprehensive sunscreens, lightweight sunscreen lotions, clear sunscreen gels.
5) Makeup series: natural radiant BB creams, long-lasting concealing foundations.
6) Household essentials series (high alcohol content): antibacterial hand sanitizing gels.
关键字： 增稠剂;乳液;凝胶;化妆品;油包水;
CURIA，前身为Albany Molecular Research, Inc. (AMRI)，成立于1991年，是一家全球性的合同研究、开发和制造组织（CDMO）。CURIA提供覆盖药物开发全谱的产品和服务，帮助合作伙伴将其想法转化为现实，从而提高商业绩效并改善患者生活。CURIA通过其在北美、欧洲和亚洲的分支机构，为全球的制药和生物技术公司提供支持。CURIA拥有深厚的科研和技术专长，提供包括生物学研究、化学过程研发、临床生产、配方开发等多方面服务。通过不断的技术创新和市场扩展，CURIA已成为生命科学领域的重要参与者。
CURIA, formerly known as Albany Molecular Research, Inc. (AMRI), founded in 1991, is a global contract research, development, and manufacturing organization (CDMO). CURIA offers a broad range of products and services across the entire drug development spectrum to assist partners in transforming their ideas into reality, thereby enhancing business performance and improving patients' lives. With branches in North America, Europe, and Asia, CURIA supports pharmaceutical and biotechnology companies worldwide. Boasting profound research and technical expertise, CURIA provides various services including biology research, chemical process R&D, clinical production, and formulation development. Through continuous technological innovation and market expansion, CURIA has become an important player in the life sciences field.