Acetylcysteine
Chinese Synonyms: phlegm easy to clean, easy to cough net, MO cough powder
Alias in English: Acetein, Acetylcystein Airbron, Broncholysin Inspir, Lysomucil Mucofilin Sol, Mucomist, Mucomyst
【Pharmacology function】 mucolytics, and its molecular formula containing thiol (-SH), the polypeptide chain and disulfide (-SS-) fracture, reduce the viscosity of sputum, sputum more easily excreted, not only can be dissolved white sputum that can dissolve purulent sputum, applies to a lot of phlegm resistance causing difficulty in breathing and expectoration difficult disorders.
Indications for postoperative expectoration difficulties, acute, chronic bronchitis, bronchiectasis, pneumonia, tuberculosis, emphysema caused by sputum viscosity and expectoration difficulties. Now also used for the treatment of idiopathic interstitial lung.
The pharmacokinetic spray inhalation onset within 1 minute, maximum duration of 5 to 10 minutes. Stripped of acetyl from homocysteine metabolism in the liver after absorption.
Dosage (1) Spray: before use, dissolve into a 10% sodium chloride injection solution, aerosol inhalation, a 3ml, on the 1st 2 or 3 times. For non-emergency situations. (2) tracheal instillation of 5% solution: first aid, and direct instillation through the trachea or endotracheal each 1 ~~ 2ml, 1, 2 or 6 times. (3) intratracheal instillation: First Aid with 5% solution with a syringe tracheal cricoid cricothyroid membrane into the tracheal cavity, each 0.5 to 2ml (baby 0.5ml, child 1ml adult 2ml).
Formulations and specifications] powder: 0.1g (bottle), 5g (bottles)
Adverse reactions
This product can cause cough, bronchospasm, nausea, vomiting and other reactions, reduction to mitigate or withdrawal. Bronchospasm available isoproterenol relief.
Intravenous this drug treatment of severe acetaminophen poisoning, the occurrence of allergic reactions, such as body rash, itching, nausea, vomiting, dizziness, and bronchospasm associated with shortness of breath and tachycardia. Other adverse reactions to angioneurotic edema, hypotension, bronchospasm.
关键字： drug treatment