盐酸贝那普利

[Chemical name] (3S)-3-[[(1S)-1-Carboxy-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid, 3-ethyl ester, monohydrochloride [Molecular Formula] C24H28N2O5•HCl [Molecular Weight] 460.96 [CAS Number] 86541-74-4 [Description] White or off white crystalline powder [Quality Standard] CP:YBH00812008 ; USP 32 [Packing] 20KG/Drum [Function and Indication] 1. It’s an ACE inhibitor used for treating moderate hypertension 2. Advantages: 1) Definite curative effect; minimal side effect, clinically treat hypertensive and congestive heart failure 2) WHO recommended as first line anti-hypertension medicine 3) Reduce ventricular afterload without increasing heart rate, improve the status of left ventricular hypertrophy and the glucose tolerance of diabetics 4) Long inhibitory activity time of ACE, quick absorption rate after oral administration and no cumulative effect after repeated doses 2. Mechanism of Action: Upon cleavage of its ester group by the liver after oral administration, benazepril is converted into its active form benazeprilat, which later competitively combines with angiotensin-converting enzyme (ACE) to reduce the activity of angiotensin-converting enzyme (ACE) and to inhibit angiotensin I from converting to angiotensin II by angiotensin-converting enzyme (ACE). In this way, Benazepril Hydrochloridec reduces blood vessel resistance to achieve the goal of lowering blood pressure

福建汇天生物药业有限公司 ( 原福建省三明制药厂 ) 创建于 1969 年 8 月，具有40年的制药历史，属大中型综合性制药企业，股份制性质。注册资金9000万元。 公司已全面通过国家GMP认证。厂区占地 10.8 万平方米，建筑面积 8.74 万平方米，现有 8 个车间。拥有抗生素原料药、粉针剂、片剂、水针剂、胶囊剂、多功能中药材提取及生化提取精制等多条生产线，并已通过国家GMP认证。公司共有八十多个品种规格的原料药及制剂。 主要的新特药及原料药品种有： 蕲蛇酶注射液蛇毒抗栓酶制剂类国家二类新药。采用生物工程技术，从蕲蛇蛇毒中分离、纯化、精制而成的凝血酶样酶，适用于急性脑梗塞的治疗。 痛血康胶囊（为国家机密处方）国家三类新药。