柳氮磺吡啶

柳氮磺吡啶基本信息MSDS用途与合成方法柳氮磺吡啶价格(试剂级)上下游产品信息中文名称:柳氮磺吡啶中文同义词:柳氮磺吡啶;柳氮磺胺吡啶-D3;5-[对-(2-吡啶胺磺酰基)苯]偶氮水杨酸;磺胺偶氮吡啶;硫氮磺吡啶;柳氮吡啶;柳氮磺胺吡啶;水杨酸偶氮磺胺吡啶英文名称:Sulfasalazine英文同义词:salicylazosulfapyridine;SALAZOSULFAPYRIDINE;SULFASALAZINE;SSZ;LABOTEST-BBLT00772281;5-(p-(2-pyridylsulfamoyl)phenylazo)salicylicacid;5-[4-(2-PYRIDYLSULFAMOYL)PHENYLAZO]SALICYLICACID;Benzoicacid,2-hydroxy-5-4-(2-pyridinylamino)sulfonylphenylazo-CAS号:599-79-1分子式:C18H14N4O5S分子量:398.4EINECS号:209-974-3相关类别:中间体;小分子抑制剂;原料药;有机原料;磺胺类产品;原料;APIs;AntibioticsforResearchandExperimentalUse;Biochemistry;Cytokinesignaling;Amines;Aromatics;Heterocycles;Sulfur&SeleniumCompounds;AZULFIDINE;OtherAPIs;API;有机化工原料;Sulfonamides(AntibioticsforResearchandExperimentalUse);Intermediates&FineChemicals;PharmaceuticalsMol文件:599-79-1.mol柳氮磺吡啶性质熔点260-265°C(dec.)(lit.)沸点689.3±65.0°C(Predicted)密度1.3742(roughestimate)折射率1.6000(estimate)储存条件Refrigerator溶解度NH4OH1M:50mg/mL,clear,red酸度系数(pKa)pKa0.6(H2Ot=20I<0.001)(Uncertain);2.4(H2Ot=20I<0.001)(Uncertain);9.7(H2Ot=20I<0.001)(Uncertain);11.8(H2Ot=20I<0.001)(Uncertain)形态powder水溶解性<0.1g/100mLat25ºCMerck14,8942BRN356241InChIKeyNCEXYHBECQHGNR-QZQOTICOSA-NCAS数据库599-79-1(CASDataBaseReference)EPA化学物质信息Salicylazosulfapyridine(599-79-1)柳氮磺吡啶用途与合成方法化学性质其外观为棕黄色微细结晶，无臭。微溶于乙醇，不溶于水、氯仿、乙醚、苯。用途肠道磺胺药，与结缔组织有特殊的亲和力，系目前治疗慢性溃疡结膜炎较好的药物生产方法2-氨基吡啶与N-乙酰氨基-苯磺酰氯反应，随后水解得到磺酰吡啶胺，即磺胺吡啶，磺胺吡啶重氮化后与水杨酸偶合、酸化即制得柳氮磺胺吡啶。